C1 Inactivator Polyclonal Antibody

Background:
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.

Research Area: Cardiovascular, Immunology

Synonyms:
SERPING1, C1IN, C1INH, C1NH, HAE1, HAE2

Immunogen: Recombinant fusion protein of human C1 Inactivator (NP_001027466.1).

Swissprot: P05155
Gene ID: 710

Calculated MW: 49 kDa/55 kDa
Observed MW: 60 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Citation(s):
https://journals.sagepub.com/doi/abs/10.1177/1945892419831108