C19orf61 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP9392a
Background:
C19orf61 is component of the SMG1C complex, a mRNA surveillance complex that recognizes and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD). In the SMG1C complex, it is required for the efficient association between SMG1 and SMG8.
Other Names:
Protein SMG9, Protein smg-9 homolog, SMG9, C19orf61
Gene Name: SMG9 (HGNC:25763)
Gene ID: 56006
Primary Accession: Q9H0W8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
C19orf61 is component of the SMG1C complex, a mRNA surveillance complex that recognizes and degrades mRNAs containing premature translation termination codons (PTCs) via the nonsense-mediated mRNA decay (NMD). The complex probably acts by associating with ribosomes during tranlation termination on mRNPs. If an exon junction complex (EJC) is located 50-55 or more nucleotides downstream from the termination codon, SMG1 phosphorylates UPF1/RENT1, triggering nonsense-mediated mRNA decay (NMD). In the SMG1C complex, it is required for the efficient association between SMG1 and SMG8.
Other Names:
Protein SMG9, Protein smg-9 homolog, SMG9, C19orf61
Gene Name: SMG9 (HGNC:25763)
Gene ID: 56006
Primary Accession: Q9H0W8
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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