C1GALT1C1 Polyclonal Antibody

Background:
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1, 3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1, 3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
HSPC067, 3-galactosyltransferase 2, Beta 1, 3 galactosyltransferase 2 , Beta1, 3 galactosyltransferase 2 , C1Gal T2 , C1Gal-T2, C1GALT1 specific chaperone 1 , C1GALT1-specific chaperone 1, C1galt1c1, C1GalT2, C1GLC, C38H2 L1, C38H2 like protein 1, C38H2-L1, C38H2-like protein 1, C38H2L1, Core 1 beta1, Core 1 beta3 galactosyltransferase specific molecular chaperone, Core 1 beta3-Gal-T2, Core 1 beta3-galactosyltransferase-specific molecular chaperone, Core 1 UDP galactose:N acetylgalactosamine alpha R beta 1, 3 galactosyltransferase 2 , COSMC , MGC19947, MST143

Immunogen: Fusion protein of human C1GALT1C1

Swissprot: Q96EU7
Gene Accession: BC011930

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.8 mg/mL
Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.