C1GALT1C1 Polyclonal Antibody

Background:
This gene encodes a type II transmembrane protein that is similar to the core 1 beta1, 3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1, 3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

Research Area: Cancer, Metabolism, Signal transduction

Synonyms:
C1GALT1C1, C1GALT2, C38H2-L1, COSMC, HSPC067, MST143, TNPS

Immunogen: Recombinant fusion protein of human C1GALT1C1 (NP_689905.1).

Swissprot: Q96EU7
Gene ID: 29071

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.