C1orf187 Antibody (C-term) Blocking peptide

Background:
Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway (By similarity).

Other Names:
Draxin {ECO:0000255|HAMAP-Rule:MF_03060}, Dorsal inhibitory axon guidance protein {ECO:0000255|HAMAP-Rule:MF_03060}, Dorsal repulsive axon guidance protein {ECO:0000255|HAMAP-Rule:MF_03060}, Neucrin, DRAXIN {ECO:0000255|HAMAP-Rule:MF_03060}, C1orf187

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13829b was selected from the C-term region of C1orf187. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: DRAXIN {ECO:0000255|HAMAP-Rule:MF_03060}

Gene ID: 374946
Primary Accession: Q8NBI3
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.