C2 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP10662a
Background:
Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. ActivatedC1 cleaves C2 into C2a and C2b. The serine proteinase C2a thencombines with complement factor 4b to create the C3 or C5convertase. Deficiency of C2 has been reported to associated withcertain autoimmune diseases and SNPs in this gene have beenassociated with altered susceptibility to age-related maculardegeneration. This gene localizes within the class III region ofthe MHC on the short arm of chromosome 6. Alternative splicingresults in multiple transcript variants encoding distinct isoforms.Additional transcript variants have been described in publicationsbut their full-length sequence has not been determined.
Other Names:
Complement C2, C3/C5 convertase, Complement C2b fragment, Complement C2a fragment, C2
Gene Name: C2
Gene ID: 717
Primary Accession: P06681
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. ActivatedC1 cleaves C2 into C2a and C2b. The serine proteinase C2a thencombines with complement factor 4b to create the C3 or C5convertase. Deficiency of C2 has been reported to associated withcertain autoimmune diseases and SNPs in this gene have beenassociated with altered susceptibility to age-related maculardegeneration. This gene localizes within the class III region ofthe MHC on the short arm of chromosome 6. Alternative splicingresults in multiple transcript variants encoding distinct isoforms.Additional transcript variants have been described in publicationsbut their full-length sequence has not been determined.
Other Names:
Complement C2, C3/C5 convertase, Complement C2b fragment, Complement C2a fragment, C2
Gene Name: C2
Gene ID: 717
Primary Accession: P06681
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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