C3G (phospho Tyr504) Polyclonal Antibody

Background:
Rap guanine nucleotide exchange factor 1(RAPGEF1) Homo sapiens This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008],

Alternative Names:
RAPGEF1, GRF2, Rap guanine nucleotide exchange factor 1, CRK SH3-binding GNRP, Guanine nucleotide-releasing factor 2, Protein C3G

Immunogen: The antiserum was produced against synthesized peptide derived from human RapGEF1 around the phosphorylation site of Tyr504. AA range:470-519

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 120

GeneID: RAPGEF1

Storage: -20°C/1 year

NOTE: For Research Use Only