C4BPB Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP16055c
Background:
This gene encodes a member of a superfamily of proteinscomposed predominantly of tandemly arrayed short consensus repeatsof approximately 60 amino acids. A single, unique beta-chainencoded by this gene assembles with seven identical alpha-chainsinto the predominant isoform of C4b-binding protein, a multimericprotein that controls activation of the complement cascade throughthe classical pathway. C4b-binding protein has a regulatory role inthe coagulation system also, mediated through the beta-chainbinding of protein S, a vitamin K-dependent protein that serves asa cofactor of activated protein C. The genes encoding both alphaand beta chains are located adjacent to each other on humanchromosome 1 in the regulator of complement activation genecluster. Alternative splicing gives rise to multiple transcriptvariants.
Other Names:
C4b-binding protein beta chain, C4BPB
Gene Name: C4BPB
Gene ID: 725
Primary Accession: P20851
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a member of a superfamily of proteinscomposed predominantly of tandemly arrayed short consensus repeatsof approximately 60 amino acids. A single, unique beta-chainencoded by this gene assembles with seven identical alpha-chainsinto the predominant isoform of C4b-binding protein, a multimericprotein that controls activation of the complement cascade throughthe classical pathway. C4b-binding protein has a regulatory role inthe coagulation system also, mediated through the beta-chainbinding of protein S, a vitamin K-dependent protein that serves asa cofactor of activated protein C. The genes encoding both alphaand beta chains are located adjacent to each other on humanchromosome 1 in the regulator of complement activation genecluster. Alternative splicing gives rise to multiple transcriptvariants.
Other Names:
C4b-binding protein beta chain, C4BPB
Gene Name: C4BPB
Gene ID: 725
Primary Accession: P20851
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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