C5 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP8577a
Catalog Number: AC-AP8577a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21866
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21866
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
Other Names:
Complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain, C5, CPAMD4
Target/Specificity:
This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids of human C5.
Antigen Region:
253-281
Antigen Type: Synthetic Peptide
Gene Name: C5
Gene ID: 727
Primary Accession: P01031
NCBI Accession: NP_001726.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
C5 is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components.
Other Names:
Complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, Complement C5 beta chain, Complement C5 alpha chain, C5a anaphylatoxin, Complement C5 alpha' chain, C5, CPAMD4
Target/Specificity:
This C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-281 amino acids of human C5.
Antigen Region:
253-281
Antigen Type: Synthetic Peptide
Gene Name: C5
Gene ID: 727
Primary Accession: P01031
NCBI Accession: NP_001726.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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