C5AR2 Polyclonal Antibody

Background:
This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.

Research Area: Signal transduction

Synonyms:
C5a anaphylatoxin chemotactic receptor C5L2, C5ARL, C5L2, E030029A11Rik, G protein coupled receptor 77, G protein coupled receptor C5L2, G-protein coupled receptor 77, GPF77, GPR77

Immunogen: Synthetic peptide of human C5AR2

Swissprot: Q9P296
Gene Accession: NP060955

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.66 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.