CA1 polyclonal, anti-human, mouse, rat

Background:
Carbonic anhydrases (CAs), also designated carbonate dehydratases or carbonate hydrolyases, form a large family of genes that encode zinc metalloenzymes of great physiologic importance. As catalysts of the reversible hydration of carbon dioxide, these enzymes participate in a variety of biologic processes, including respiration, acid-base balance, bone resorption and calcification as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. Genes in the α-carbonic anhydrase family encode either active carbonic anhydrase isozymes or "acatalytic" (devoid of CO2 hydration activity) carbonic anhydrase-related proteins. Human CA I (CA1) is encoded by the CA1 gene, which maps to a region on chromosome 8 that harbors a cluster of CA genes. CA I localizes to the cytoplasm and research indicates that a severe deficiency of CA I does not result in any obvious hematological or renal consequences.

Alternative Name:
CAB, CA-I, CA1, CA 1, CA I, CA-I, CA1, CAB, CAH1, CAI, CAN, Car 1, Car1, Carbonate dehydratase I, Carbonic anhydrase 1, Carbonic anhydrase A, Carbonic anhydrase B, Carbonic anhydrase B, formerly, Carbonic anhydrase I, Carbonic dehydratase, ECK0125, JW0122, yadF,

Application Dilution:
WB:1:500-1:2,000
IHC:1:50-1:200

Specificity: CA1 polyclonal antibody detects endogenous levels of CA1 protein.

Immunogen:
Recombinant protein within human Carbonic Anhydrase I aa 1-200.

MW: 29 kDa

Swiss-Prot: P00915(Human) P13634(Mouse)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.