CA19-9/Sialyl Lewisa (clone CA19.9/1390R), anti-human
€0.00
In stock
SKU
AC-AH13692
Catalog Number: AC-AH13692
Size: 20 µg, 100 µg
Isotype: Rabbit
Clone Name: CA19.9/1390R
Applications: IHC-P, IF, FC
Datasheet
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Size: 20 µg, 100 µg
Isotype: Rabbit
Clone Name: CA19.9/1390R
Applications: IHC-P, IF, FC
Datasheet
Request Information
Background:
CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Other Names:
CA19.9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a
Antigen Type:
Recombinant protein
Primary Accession:
Other Accession:
CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Other Names:
CA19.9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a
Antigen Type:
Recombinant protein
Primary Accession:
Other Accession:
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