CA4 Polyclonal Antibody

Background:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport.

Research Area: Neuroscience

Synonyms:
CA IV, CA4, CAH4, CAIV, Car4, Carbonate dehydratase IV, Carbonic anhydrase 4, Carbonic dehydratase, Carbonic dehydratase IV, EC 4.2.1.1, Retinitis pigmentosa 17 (autosomal dominant), RP17

Immunogen: Recombinant protein of human CA4

Swissprot: P22748
Gene Accession: BC057792

Calculated MW: 35 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-17247/sc-25597