CABIN1 Polyclonal Antibody

Background:
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.

Research Area: Cancer, Signal transduction

Synonyms:
A330070M20Rik, Cabin 1, CABIN, Cabin1, CAIN, Calcineurin binding protein cabin 1, Calcineurin inhibitor, Calcineurin-binding protein cabin-1, KIAA0330, PPP3IN

Immunogen: Synthetic peptide of human CABIN1

Swissprot: Q9Y6J0
Gene Accession: NP036427

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.