CACNA1A polyclonal (Center), anti-human

CACNA1A polyclonal (Center), anti-human

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In stock
SKU
AC-AP21701c
Catalog Number: AC-AP21701c
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB53551
Applications: WB
Datasheet

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Background:
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin- IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DHP), and omega-conotoxin-GVIA (omega-CTx-GVIA).

Other Names:
Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Brain calcium channel I, BI, Calcium channel, L type, alpha-1 polypeptide isoform 4, Voltage-gated calcium channel subunit alpha Cav21, CACNA1A, CACH4, CACN3, CACNL1A4

Target/Specificity:
This CACNA1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 898-932 amino acids from the Central region of human CACNA1A.

Antigen Region:
898-932

Gene Name: CACNA1A (HGNC:1388)
Gene ID: 773
Primary Accession: O00555
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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