CACNA1C polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CACNA1C is also known as TS, LQT8, CACH2, CACN2, CaV1.2, CCHL1A1, CACNL1A1. It is mapped to 12p13.3. This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta and beta subunits in a 1:1:1 ratio. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.

Description:
Rabbit IgG polyclonal antibody for Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
alpha-1 polypeptide antibody, cardiac muscle antibody, isoform 1 antibody, L type antibody, CAC1C_HUMAN antibody, CACH 2 antibody, CACH2 antibody, CACN 2 antibody, CACN2 antibody, CACNA1C antibody, CACNL1A1 antibody, Calcium channel antibody, Calcium channel cardic dihydropyridine sensitive alpha 1 subunit antibody, Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle antibody, Calcium channel voltage dependent L type alpha 1C subunit antibody, CaV1.2 antibody, CCHL1A1 antibody, DHPR alpha 1 antibody, DHPR alpha 1 subunit antibody, LQT8 antibody, TS antibody, Voltage dependent L type calcium channel alpha 1C subunit antibody, Voltage dependent L type calcium channel subunit alpha 1C antibody, Voltage gated calcium channel alpha subunit Cav1.2 antibody, Voltage gated calcium channel subunit alpha Cav1.2 antibody, Voltage gated L type calcium channel Cav1.2 alpha 1 subunit, splice variant 10* antibody, Voltage-dependent L-type calcium channel subunit alpha-1C antibody, Voltage-gated calcium channel subunit alpha Cav1.2 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CACNA1C recombinant protein (Position: E1933-H2026). Human CACNA1C shares 88.3% amino acid (aa) sequence identity with both mouse and rat CACNA1C.E.coli-derived human CACNA1C recombinant protein (Position: E1933-H2026). Human CACNA1C shares 88.3% amino acid (aa) sequence identity with both mouse and rat CACNA1C.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.