CACNG3 polyclonal, anti-human,Rat

Background:
Regulates the trafficking to the somatodendritic compartment and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

Alternative Name:
TARP gamma-3, CACNG3, CACNG 3, Cacng2, CACNG3, Calcium channel voltage dependent gamma subunit 3, CCG3, Neuronal voltage gated calcium channel gamma 3 subunit, Neuronal voltage-gated calcium channel gamma-3 subunit, TARP gamma-3, Transmembrane AMPAR regulatory protein gamma-3, Voltage dependent calcium channel gamma 3 subunit, Voltage gated calcium channel gamma subunit, Voltage-dependent calcium channel gamma-3 subunit,

Application Dilution:
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: CACNG3 polyclonal antibody detects endogenous levels of CACNG3 protein.

Immunogen:
Synthetic peptide within rat CACNG3 aa 200-250.

MW: Predicted band size 36 kDa

Swiss-Prot: O60359(Human) Q8VHX0(Rat)

Purification & Purity:
Peptide affinity purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.