CACNG7 Antibody (C-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP9136b
Background:
The mouse protein stargazin is one of five subunits comprising neuronal voltage-gated calcium channels. It is thought to stabilize the calcium channel in an inactive (closed) state. Mutations in stargazin have been associated with absence seizures, also known as petit-mal or spike-wave seizures. CACNG7 is structurally similar to the mouse stargazin protein and is a member of the neuronal calcium channel gamma subunit protein family. It appears unlikely that CACNG7 is part of a functional calcium channel. Rather, it appears to inhibit the expression of a specific calcium channel subunit.
Other Names:
Voltage-dependent calcium channel gamma-7 subunit, Neuronal voltage-gated calcium channel gamma-7 subunit, Transmembrane AMPAR regulatory protein gamma-7, TARP gamma-7, CACNG7
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9136b was selected from the C-term region of human CACNG7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CACNG7
Gene ID: 59284
Primary Accession: P62955
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The mouse protein stargazin is one of five subunits comprising neuronal voltage-gated calcium channels. It is thought to stabilize the calcium channel in an inactive (closed) state. Mutations in stargazin have been associated with absence seizures, also known as petit-mal or spike-wave seizures. CACNG7 is structurally similar to the mouse stargazin protein and is a member of the neuronal calcium channel gamma subunit protein family. It appears unlikely that CACNG7 is part of a functional calcium channel. Rather, it appears to inhibit the expression of a specific calcium channel subunit.
Other Names:
Voltage-dependent calcium channel gamma-7 subunit, Neuronal voltage-gated calcium channel gamma-7 subunit, Transmembrane AMPAR regulatory protein gamma-7, TARP gamma-7, CACNG7
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9136b was selected from the C-term region of human CACNG7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CACNG7
Gene ID: 59284
Primary Accession: P62955
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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