CADH1 polyclonal, anti-human, mouse

Background:
Cadherins are calcium-dependent cell adhesion proteins . They preferentially interact with themselves in a homophilic manner in connecting cells; E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.2 Publications

Synonyms: CDH1, Cadherin-1, CDHE, UVO, ECAD, Arc-1, CD324, LCAM

Cellular Location: Cell membrane

Immunogen:
A synthetic peptide of human CADH1

Gene Symbol: CADH1

Gene ID: 999

Swiss prot: P12830

Calculated MW: 97kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.