Cadherin-16 Polyclonal Antibody

Cadherin-16 Polyclonal Antibody

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In stock
SKU
ELK-ES1822
Catalog Number: ELK-ES1822
Reactivity: Human
Applications: WB, IHC-p, IF, ELISA
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Background:
cadherin 16(CDH16) Homo sapiens This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011],

Alternative Names:
CDH16, Cadherin-16, Kidney-specific cadherin, Ksp-cadherin

Immunogen: The antiserum was produced against synthesized peptide derived from human CDH16. AA range:780-829

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 90

GeneID: CDH16

Storage: -20°C/1 year

NOTE: For Research Use Only
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