CADM3 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61572
Background:
Immunoglobulin superfamily member 4B (Cell adhesion molecule 3, Nectinlike protein 1) is a nectin family gene product that contains 2 Ig-like C2-type (immunoglobulin-like) domains and an Ig-like V-type (immunoglobulin-like) domain. IGSF4B is a single-pass type I membrane protein that localizes to cellcell interacting sites along the plasma membrane. IGSF4B functions as a cell adhesion molecule at cell-cell junctions. IGSF4B can be found as a homodimer and has a dual calcium-independent adhesion function; a homophilic cell-cell interaction and a heterophilic cell-cell interaction involving IGSF4, Nectin 1 and Nectin 3. IGSF4B may also interact with EPB41L1 which has a potential for regulating structure or function of cell-cell junctions by similarity. Isoform 1 is expressed in adult and fetal brain. Isoform 2 is highly expressed in the cerebellum but is also weakly expressed in placenta. IGSF4B has been found to be markedly over-expressed in glioma cell lines and prostate cancer cell lines.
Alternative Name:
Cell adhesion molecule 3, Brain immunoglobulin receptor, Immunoglobulin superfamily member 4B, IgSF4B, Nectin-like protein 1, NECL-1, Synaptic cell adhesion molecule 3, SynCAM3, TSLC1-like protein 1, TSLL1
Application Dilution: WB: 1:500~1:1000
Specificity: CADM3 polyclonal antibody detects endogenous levels of CADM3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 144-188 of Human CADM3
MW: ~ 50 kDa
Swis Prot.: Q8N126
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Immunoglobulin superfamily member 4B (Cell adhesion molecule 3, Nectinlike protein 1) is a nectin family gene product that contains 2 Ig-like C2-type (immunoglobulin-like) domains and an Ig-like V-type (immunoglobulin-like) domain. IGSF4B is a single-pass type I membrane protein that localizes to cellcell interacting sites along the plasma membrane. IGSF4B functions as a cell adhesion molecule at cell-cell junctions. IGSF4B can be found as a homodimer and has a dual calcium-independent adhesion function; a homophilic cell-cell interaction and a heterophilic cell-cell interaction involving IGSF4, Nectin 1 and Nectin 3. IGSF4B may also interact with EPB41L1 which has a potential for regulating structure or function of cell-cell junctions by similarity. Isoform 1 is expressed in adult and fetal brain. Isoform 2 is highly expressed in the cerebellum but is also weakly expressed in placenta. IGSF4B has been found to be markedly over-expressed in glioma cell lines and prostate cancer cell lines.
Alternative Name:
Cell adhesion molecule 3, Brain immunoglobulin receptor, Immunoglobulin superfamily member 4B, IgSF4B, Nectin-like protein 1, NECL-1, Synaptic cell adhesion molecule 3, SynCAM3, TSLC1-like protein 1, TSLL1
Application Dilution: WB: 1:500~1:1000
Specificity: CADM3 polyclonal antibody detects endogenous levels of CADM3 protein.
Immunogen:
Synthetic peptide, corresponding to amino acids 144-188 of Human CADM3
MW: ~ 50 kDa
Swis Prot.: Q8N126
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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