CD133 polyclonal, anti-human, mouse
€470.00
In stock
SKU
AC-AP73375
Background:
May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol- containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
Other Names:
PROM1; Prominin-1; Antigen AC133; Prominin-like protein 1; CD133
Antigen Type: synthetic peptide
Antigen Type: PROM1
Gene ID: 8842
Primary Accession: O43490
May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol- containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439).
Other Names:
PROM1; Prominin-1; Antigen AC133; Prominin-like protein 1; CD133
Antigen Type: synthetic peptide
Antigen Type: PROM1
Gene ID: 8842
Primary Accession: O43490
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