Calcineurin Substrate Peptide

Protein Family: Enzymes

Pathway and Disease: Signal Transduction, Cell Growth and Death, Immune System, Nervous and Sensory Systems, Development and Behavior, Neurodegenerative Disorders

Alternate Names: Calcineurin; cAMP-dependent protein kinase type-II-alpha regulatory subunit

Accession No.: P00515

Description:
The calcineurin substrate peptide corresponds to a sequence from the regulatory RII subunit of cAMP-dependent protein kinase. Calcineurin substrate can be used for assaying protein phosphatase-2B (calcineurin) activity.

Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.

MW: 2112.4 g/mol

Sequence:
H-Asp-Leu-Asp-Val-Pro-Ile-Pro-Gly-Arg-Phe-Asp-Arg-Arg-Val-Ser-Val-Ala-Ala-Glu-OH or H-DLDVPIPGRFDRRVSVAAE-OH

Composition:
C92H150N28O29

Purity:
> 95% by HPLC

Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.