CALCOCO1 Polyclonal Antibody

Background:
CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/β-catenin signaling pathway. CALCOCO1 exists as three alternatively spliced isoforms (termed Q9P1Z2-1, 2 and 3), which are encoded by genes mapping to human chromosome 12q13.13 and mouse chromosome 15 F3.

Research Area: Epigenetics and Nuclear Signaling, Signal transduction

Synonyms:
Calcium binding and coiled coil domain 1, CALCOCO1, Calphoglin , Coiled coil coactivator protein, Coiled coil leucine zipper coactivator 1 , Coiled coil transcriptional coactivator , Inorganic pyrophosphatase activator , KIAA1536 , PP13275 , Sarcoma antigen NY-SAR-3

Immunogen: Fusion protein of human CALCOCO1

Swissprot: Q9P1Z2
Gene Accession: BC003177

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.72 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.