CALD1 Polyclonal Antibody

Background:
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
CALD1, CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22, caldesmon

Immunogen: Recombinant fusion protein of human CALD1 (NP_004333.1).

Swissprot: Q05682
Gene ID: 800

Calculated MW: 61 kDa/62 kDa/64 kDa/65 kDa/93 kDa
Observed MW: 85 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.