Caldesmon polyclonal, anti-human
€0.00
In stock
SKU
AC-AP22429a
Catalog Number: AC-AP22429a
Size: 50 µl, 200 µl
Isotype: Rabbit Ig
Clone Name: R03777
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit Ig
Clone Name: R03777
Applications: WB
Datasheet
Request Information
Background:
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity).
Other Names:
Caldesmon, CDM, CALD1, CAD, CDM
Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.
Antigen Type: Recombinant Protein
Gene Name: CALD1
Gene ID: 800
Primary Accession: Q05682
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity).
Other Names:
Caldesmon, CDM, CALD1, CAD, CDM
Target/Specificity:
This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from human.
Antigen Type: Recombinant Protein
Gene Name: CALD1
Gene ID: 800
Primary Accession: Q05682
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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