Calgranulin B (Macrophage Marker) (clone CAGB/426 ), anti-human

Calgranulin B (Macrophage Marker) (clone CAGB/426 ), anti-human

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In stock
SKU
AC-AH12287
Catalog Number: AC-AH12287
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: CAGB/426
Applications: IHC-P, IF, FC
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Background:
Recognizes a 12-14kDa doublet of Calgranulin A/B (also known as S100A8/A9 or MRP-8/14); expressed by granulocytes, monocytes and by tissue macrophages.ĀThe protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of this protein is associated with the disease cystic fibrosis. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.

Other Names:
Protein S100-A9, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9, S100A9, CAGB, CFAG, MRP14

Gene Name: S100A9 {ECO:0000303|PubMed:12626582, ECO:0000312|HGNC:HGNC:10499}
Gene ID: 6280
Primary Accession: P06702
Other Accession: 6280 (S100A9 / Calgranulin B / MRP-14), 112405 (S100A9 / Calgranulin B / MRP-14)
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