CALML6 Polyclonal Antibody

Background:
The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), a universal calcium sensor. CaM directly modulates the activity of protein kinases and phosphatases, ion channels and nitric oxide synthetases and is generally involved in such diverse processes as cell proliferation, endocytosis, cellular adhesion, protein turnover and smooth muscle contraction. CALML6 (calmodulin-like 6), also known as CAGLP or CALGP, is a 181 amino acid protein that contains four EF-hand domains and shares functional similarity with CaM. Localized to both the nucleus and the cytoplasm, CALML6 is expressed in heart, prostate, ovary, thymus and bone marrow where it may regulate calcium-related events.

Research Area: Signal transduction

Synonyms:
CAGLP, Calglandulin-like protein, CALGP, CALL6, CALML6, Calmodulin like 6, Calmodulin-like protein 6, EF-hand protein, OTTHUMP00000001117, OTTHUMP00000179025, RP1-140A9.2

Immunogen: Synthetic peptide of human CALML6

Swissprot: Q8TD86
Gene Accession: NP619650

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.