Calnexin Rabbit pAb

Background:
Calnexin is a chaperone, characterized by assisting protein folding and quality control, ensuring that only properly folded and assembled proteins proceed further along the secretory pathway. Calnexin is a integral protein (that appears variously as a 90kDa, 80kDa or 75kDa band on western blotting depending on the source of the antibody) of the endoplasmic reticulum (ER). It consists of a large (50 kDa) N-terminal calcium-binding lumenal domain, a single transmembrane helix and a short (90 residues), acidic cytoplasmic tail.

Cellular localization: Endoplasmic reticulum membrane,Melanosome.

Specificity: Human

Alternative Names:
CANX antibody, CNX antibody, FLJ26570 antibody, IP90 antibody, P90 antibody

Immunogen: Recombinant Protein

Isotype: Rabbit Polyclonal IgG

Concentration: 1mg/ml

Recommended dilutions: WB 1:1,000-2,000, IHC 1:200-500

Observed band: 75,80,90kDa

GeneID: 821

Swiss-Prot No.: P27824

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Store at -20°C. Avoid repeated freeze-thaw cycles.

NOTE: For Research Use Only