Calpain 2 (Phospho Ser50) Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
The calpains| calcium-activated neutral proteases| are nonlysosomal| intracellular cysteine proteases. The mammalian calpains include ubiquitous| stomach-specific| and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large| catalytic subunits associated with a common small| regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme| calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell biology, Metabolism, Signal transduction

Synonyms: Calpain 2 , Phospho Ser50, Calpain-2 catalytic subunit, EC 3.4.22.53, Calcium-activated neutral proteinase 2, CANP 2, Calpain M-type, Calpain large polypeptide L2, Calpain-2 large subunit, Millimolar-calpain, M-calpain

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year