Calpain 2 Picoband polyclonal, anti-human, mouse, rat

Calpain 2 Picoband polyclonal, anti-human, mouse, rat

€455.00
In stock
SKU
AC-ABO13013
Catalog Number: AC-ABO13013
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB, IHC-P
Datasheet
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Description: Rabbit IgG polyclonal antibody for Calpain-2 catalytic subunit(CAPN2) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

Protein Function:
Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). .

Other Names: Calpain-2 catalytic subunit, 3.4.22.53, Calcium-activated neutral proteinase 2, CANP 2, Calpain M-type, Calpain large polypeptide L2, Calpain-2 large subunit, Millimolar-calpain, M-calpain, CAPN2, CANPL2

Subcellular Localization: Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding.

Tissue Specificity: Ubiquitous.

Gene ID: 824

Immunogen: E. coli-derived human Calpain 2 recombinant protein (Position: R500-L700). Human Calpain 2 shares 93.5% and 92.5% amino acid (aa) sequence identity with mouse and rat Calpain 2, respectively.

Calculated MW: 79995

Purification: Immunogen affinity purified.

Format: Lyophilized

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
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