Calponin 2 rabbit polyclonal, anti-human, mouse

Backgroud: The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.,similarity:Belongs to the calponin family.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 3 calponin-like repeats.,tissue specificity:Heart and smooth muscle.,

Synonyms: CNN2, Calponin-2, Calponin H2, smooth muscle, Neutral calponin

Gene Name: CNN2

Gene ID: 1265

SwissProt ID: Q99439

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.