Calretinin polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Calretinin, also known as 29 kDa calbindin, is a vitamin D-dependent calcium-binding protein involved in calcium signaling. In humans, the calretinin protein is encoded by the CALB2 gene. This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. Calretinin is mapped to 16q22.2. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers.

Description:
Rabbit IgG polyclonal antibody for Calretinin (CALB2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
29 kDa calbindin antibody, CAB 29 antibody, CAB29 antibody, CAL 2 antibody, CAL2 antibody, CALB 2 antibody, CALB2 antibody, CALB2_HUMAN antibody, Calbindin 2 29kDa antibody, Calbindin 2 antibody, Calbindin D29K antibody, Calbindin2 antibody, Calretinin antibody, CR antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminal of human Calretinin(234-262aa EMNIQQLTNYRKSVMSLAEAGKLYRKDLE), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.