Calretinin polyclonal, anti-human, mouse, rat

Background:
Calbindin D28K and Calretinin (also designated CR or 29 kDa Calbindin) are two closely related intracellular calcium-binding proteins belonging to the Troponin-C superfamily. Initially isolated from chick retina, Calretinin shares 58% identical residues with human Calbindin D28K. Calretinin is expressed in the brain and is particularly abundant in auditory neurons with precisely timed discharges. Neurons in the nucleus accumbens containing Calretinin all possess nuclear indentations. Calretinin-immunoreactive boutons form asymmetrical and symmetrical synaptic specializations on spines, dendrites and somata. The symmetrical synaptic specializations have medium-sized spiny neurons and contact other Calretinin-immunoreactive somata. Calretinin is widely used as a immunocytochemical marker for mesothelioma.

Alternative Name:
CR, CALB2, CAB29, 29 kDa calbindin, CAB 29, CAB29, CAL 2, CAL2, CALB 2, CALB2, CALB2, Calbindin 2 29kDa, Calbindin 2, Calbindin D29K, Calbindin2, Calretinin, CR,

Application Dilution:
WB:1:500
IHC:1:50-1:200

Specificity: Calretinin polyclonal antibody detects endogenous levels of Calretinin protein.

Immunogen:
Recombinant protein

MW: 31 kDa

Swiss-Prot: P22676(Human) Q08331(Mouse) P47728(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.