CaMK2a Peptide
€133.00
In stock
SKU
300117
Protein Family: Enzymes, Protein Kinases
Pathway and Disease: Development and Behavior, Nervous and Sensory Systems, Signal Transduction
Alternate Names: CaMK2a; Calcium/calmodulin-dependent protein kinase type II alpha chain; CaM-kinase II alpha chain; CaM kinase II subunit alpha; CaMK-II subunit alpha
Accession No.: Q9UQM7
Description:
CaMK2a (CAMKII alpha, CaM Kinase 2 alpha) is a prominent Ser/Thr kinase in the central nervous system thatfunctions in long-term potentiation and neurotransmitter release. A member of the NMDAR signaling complex at the excitatory synapse, it regulates NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. CAMK2a is composed of alpha, beta, gamma, and delta chains that assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. CaMK2a interacts with BAALC, MPDZ, SYN1, CAMK2N2 and SYNGAP1.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 11400 g/mol (MAP8 peptide)
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 250569 is selected from a sequence within the C-term region of human CaMK2a. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Pathway and Disease: Development and Behavior, Nervous and Sensory Systems, Signal Transduction
Alternate Names: CaMK2a; Calcium/calmodulin-dependent protein kinase type II alpha chain; CaM-kinase II alpha chain; CaM kinase II subunit alpha; CaMK-II subunit alpha
Accession No.: Q9UQM7
Description:
CaMK2a (CAMKII alpha, CaM Kinase 2 alpha) is a prominent Ser/Thr kinase in the central nervous system thatfunctions in long-term potentiation and neurotransmitter release. A member of the NMDAR signaling complex at the excitatory synapse, it regulates NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. CAMK2a is composed of alpha, beta, gamma, and delta chains that assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. CaMK2a interacts with BAALC, MPDZ, SYN1, CAMK2N2 and SYNGAP1.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 11400 g/mol (MAP8 peptide)
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 250569 is selected from a sequence within the C-term region of human CaMK2a. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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