CAMKK2 polyclonal (C-term), anti-human

CAMKK2 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP7117b
Catalog Number: AC-AP7117b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB12560
Applications: IHC-P, WB
Datasheet

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Background:
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.

Other Names:
Calcium/calmodulin-dependent protein kinase kinase 2, CaM-KK 2, CaM-kinase kinase 2, CaMKK 2, Calcium/calmodulin-dependent protein kinase kinase beta, CaM-KK beta, CaM-kinase kinase beta, CaMKK beta, CAMKK2, CAMKKB, KIAA0787

Target/Specificity:
This CAMKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-512 amino acids from the C-terminal region of human CAMKK2.

Antigen Region:
483-512

Antigen Type: Synthetic Peptide

Gene Name: CAMKK2
Gene ID: 10645
Primary Accession: Q96RR4
NCBI Accession: NP_001257414.1;NP_001257415.1;NP_006540.3;NP_705719.2;NP_705720.1;NP_757363.1;NP_757364.1;NP_757365.1;NP_757380.1
Other Accession: O88831; Q8C078
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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