CAPN6 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP12546c
Background:
Calpains are ubiquitous, well-conserved family ofcalcium-dependent, cysteine proteases. The calpain proteins areheterodimers consisting of an invariant small subunit and variablelarge subunits. The large subunit possesses a cysteine proteasedomain, and both subunits possess calcium-binding domains. Calpainshave been implicated in neurodegenerative processes, as theiractivation can be triggered by calcium influx and oxidative stress.The protein encoded by this gene is highly expressed in theplacenta. Its C-terminal region lacks any homology to thecalmodulin-like domain of other calpains. The protein lackscritical active site residues and thus is suggested to beproteolytically inactive. The protein may play a role in tumorformation by inhibiting apoptosis and promoting angiogenesis.
Other Names:
Calpain-6, Calpain-like protease X-linked, Calpamodulin, CalpM, CAPN6, CALPM, CANPX
Gene Name: CAPN6
Gene ID: 827
Primary Accession: Q9Y6Q1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Calpains are ubiquitous, well-conserved family ofcalcium-dependent, cysteine proteases. The calpain proteins areheterodimers consisting of an invariant small subunit and variablelarge subunits. The large subunit possesses a cysteine proteasedomain, and both subunits possess calcium-binding domains. Calpainshave been implicated in neurodegenerative processes, as theiractivation can be triggered by calcium influx and oxidative stress.The protein encoded by this gene is highly expressed in theplacenta. Its C-terminal region lacks any homology to thecalmodulin-like domain of other calpains. The protein lackscritical active site residues and thus is suggested to beproteolytically inactive. The protein may play a role in tumorformation by inhibiting apoptosis and promoting angiogenesis.
Other Names:
Calpain-6, Calpain-like protease X-linked, Calpamodulin, CalpM, CAPN6, CALPM, CANPX
Gene Name: CAPN6
Gene ID: 827
Primary Accession: Q9Y6Q1
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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