CAPN9 antibody (clone 3A6), anti-human
€435.00
In stock
SKU
AC-AT1390a
Catalog Number: AC-AT1390a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC, E
Request Information AC-AT1390a">Request Information
Background:
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Calpain-9, 3422-, Digestive tract-specific calpain, New calpain 4, nCL-4, Protein CG36, CAPN9, NCL4
Antigen Type:
Recombinant Protein
Gene Name: CAPN9
Gene ID: 10753
NCBI Accession: NP_006606.1;NP_057536.1
Primary Accession: O14815
Other Accession: NM_006615
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Calpain-9, 3422-, Digestive tract-specific calpain, New calpain 4, nCL-4, Protein CG36, CAPN9, NCL4
Antigen Type:
Recombinant Protein
Gene Name: CAPN9
Gene ID: 10753
NCBI Accession: NP_006606.1;NP_057536.1
Primary Accession: O14815
Other Accession: NM_006615
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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