CAPNS1 antibody (clone 3C4), anti-human, rat
€435.00
In stock
SKU
AC-AT1391a
Catalog Number: AC-AT1391a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF
Request Information AC-AT1391a">Request Information
Background:
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
Other Names:
Calpain small subunit 1, CSS1, Calcium-activated neutral proteinase small subunit, CANP small subunit, Calcium-dependent protease small subunit, CDPS, Calcium-dependent protease small subunit 1, Calpain regulatory subunit, CAPNS1, CAPN4, CAPNS
Antigen Type:
Recombinant Protein
Gene Name: CAPNS1
Gene ID: 826
NCBI Accession: NP_001003962.1;NP_001740.1
Primary Accession: P04632
Other Accession: BC000592
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.
Other Names:
Calpain small subunit 1, CSS1, Calcium-activated neutral proteinase small subunit, CANP small subunit, Calcium-dependent protease small subunit, CDPS, Calcium-dependent protease small subunit 1, Calpain regulatory subunit, CAPNS1, CAPN4, CAPNS
Antigen Type:
Recombinant Protein
Gene Name: CAPNS1
Gene ID: 826
NCBI Accession: NP_001003962.1;NP_001740.1
Primary Accession: P04632
Other Accession: BC000592
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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