CAPNS1 Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13301a
Background:
Calpains are a ubiquitous, well-conserved family ofcalcium-dependent, cysteine proteases. Calpain families have beenimplicated in neurodegenerative processes, as their activation canbe triggered by calcium influx and oxidative stress. Calpain I andII are heterodimeric with distinct large subunits associated withcommon small subunits, all of which are encoded by different genes.This gene encodes a small subunit common to both calpain I and IIand is associated with myotonic dystrophy. Two transcript variantsencoding the same protein have been identified for this gene.
Other Names:
Calpain small subunit 1, CSS1, Calcium-activated neutral proteinase small subunit, CANP small subunit, Calcium-dependent protease small subunit, CDPS, Calcium-dependent protease small subunit 1, Calpain regulatory subunit, CAPNS1, CAPN4, CAPNS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13301a was selected from the N-term region of CAPNS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CAPNS1
Gene ID: 826
Primary Accession: P04632
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Calpains are a ubiquitous, well-conserved family ofcalcium-dependent, cysteine proteases. Calpain families have beenimplicated in neurodegenerative processes, as their activation canbe triggered by calcium influx and oxidative stress. Calpain I andII are heterodimeric with distinct large subunits associated withcommon small subunits, all of which are encoded by different genes.This gene encodes a small subunit common to both calpain I and IIand is associated with myotonic dystrophy. Two transcript variantsencoding the same protein have been identified for this gene.
Other Names:
Calpain small subunit 1, CSS1, Calcium-activated neutral proteinase small subunit, CANP small subunit, Calcium-dependent protease small subunit, CDPS, Calcium-dependent protease small subunit 1, Calpain regulatory subunit, CAPNS1, CAPN4, CAPNS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13301a was selected from the N-term region of CAPNS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CAPNS1
Gene ID: 826
Primary Accession: P04632
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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