CAPNS1 Polyclonal Antibody

Background:
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

Research Area: Cancer, Cell Biology, Metabolism, Signal Transduction

Synonyms:
30K, Calcium activated neutral proteinase, Calcium activated neutral proteinase small subunit, Calcium dependent protease small subunit 1, Calcium dependent protease small subunit, Calcium-activated neutral proteinase small subunit, Calcium-dependent protease small subunit 1, Calcium-dependent protease small subunit, Calpain 4, Calpain 4 small subunit (30K), Calpain 4 small subunit, Calpain regulatory subunit, Calpain small polypeptide, Calpain small subunit 1, Calpain4, CalpainS1, CANP, CANP small subunit, CANPS, CAPN 4, CAPN S1, CAPN4, CAPNS 1, CAPNS, Capns1, CDPS, CPNS1, CSS 1, CSS1

Immunogen: Recombinant protein of human CAPNS1

Swissprot: P04632
Gene Accession: BC000592

Calculated MW: 28 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-7528/sc-7529/sc-30065