CAPRIN1 Polyclonal Antibody

Background:
Caprin-1is aproteinthat in humans is encoded by theCAPRIN1gene. May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. May form homomultimers. Directly interacts with G3BP1 in cytoplasmic RNA granules. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.

Research Area: Cell Biology

Synonyms:
CAPRIN1, GPIAP1, GPIP137, GRIP137, M11S1, RNG105, p137GPI, caprin-1

Immunogen: Recombinant protein of human CAPRIN1

Swissprot: Q14444
Gene ID: 4076

Calculated MW: 76 kDa/78 kDa
Observed MW: 120 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:100-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.