CARD10 polyclonal (Center), anti-human

CARD10 polyclonal (Center), anti-human

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In stock
SKU
AC-AP14373C
Catalog Number: AC-AP14373C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34247
Applications: WB
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Background:
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).

Other Names:
Caspase recruitment domain-containing protein 10, CARD-containing MAGUK protein 3, Carma 3, CARD10, CARMA3

Target/Specificity:
This CARD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the Central region of human CARD10.

Antigen Region:
518-546

Antigen Type: Synthetic Peptide

Gene Name: CARD10
Gene ID: 29775
Primary Accession: Q9BWT7
NCBI Accession: NP_055365.2
Other Accession: NP_055365.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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