CARD11 polyclonal, anti-human, mouse

Background:
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation.

Synonyms: PPBL, BENTA, BIMP3, IMD11, CARMA1

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human CARD11

Gene Symbol: CARD11

Gene ID: 84433

Swiss prot: Q9BXL7

Calculated MW: 133kDa

Recommended dilution:
IHC 1:20-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.