CARD12 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
NLR family CARD domain-containing protein 4, also known as CARD12, is a protein that in humans is encoded by the NLRC4 gene. It is mapped to 2p22.3. This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.

Description:
Rabbit IgG polyclonal antibody for NLR family CARD domain-containing protein 4 (NLRC4) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
and NACHT-containing protein antibody, CARD 12 antibody, CARD antibody, CARD LRR and NACHT containing protein 1 antibody, CARD LRR and NACHT containing protein antibody, CARD12 antibody, Caspase recruitment domain containing protein 12 antibody, Caspase recruitment domain family member 12 antibody, Caspase recruitment domain-containing protein 12 antibody, CLAN 1 antibody, CLAN A antibody, CLAN antibody, CLAN B antibody, CLAN C antibody, CLAN D antibody, Clan protein antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR 2.1 antibody, CLR2.1 antibody, ICE protease activating factor antibody, Ice protease-activating factor antibody, IPAF antibody, LRR antibody, NLR family CARD domain containing 4 antibody, NLR family CARD domain-containing protein 4 antibody, NLRC 4 antibody, NLRC4 antibody, NLRC4_HUMAN antibody, NOD like receptor C4 antibody, Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 4 antibody, UNQ6189/PRO20215 antibody.

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human CARD12 (838-874aa KILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDR), different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.