CARD17 Polyclonal Antibody

Background:
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.

Research Area: Cell biology

Synonyms:
CAR17, CARD 17, CARD17, Caspase 1 inhibitor, Caspase recruitment domain containing protein 17, Caspase recruitment domain-containing protein 17, Caspase-1 inhibitor INCA, Caspase1 inhibitor, Inhibitory caspase recruitment domain (CARD) protein, Inhibitory caspase recruitment domain protein

Immunogen: Synthetic peptide of human CARD17

Swissprot: Q5XLA6
Gene Accession: NP_001007233

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.