CARD4 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. NOD1 is a member of NOD-like receptor protein family and is a close relative of NOD2. NOD1 is mapped to 7p14.3. It recognizes bacterial molecules and stimulates an immune reaction. NOD1 protein contains a caspase recruitment domain (CARD). This gene is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants, and mediates innate and acquired immunity by recognizing bacterial molecules containing D-glutamyl-meso-diaminopimelic acid (iE-DAP) moiety. What wore, it has been shown that NOD1 can sense cytosolic microbial products by monitoring the activation state of small Rho GTPases.

Description:
Rabbit IgG polyclonal antibody for Nucleotide-binding oligomerization domain-containing protein 1 (NOD1) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
CARD 4 antibody, CARD4 antibody, Caspase recruitment domain 4 antibody, Caspase recruitment domain containing protein 4 antibody, Caspase recruitment domain family member 4 antibody, Caspase recruitment domain protein 4 antibody, Caspase recruitment domain-containing protein 4 antibody, CLR 7.1 antibody, CLR7.1 antibody, NLR family CARD domain containing 1 antibody, NLRC 1 antibody, NLRC1 antibody, NOD 1 antibody, Nod1 antibody, NOD1 protein antibody, NOD1_HUMAN antibody, Nucleotide binding oligomerization domain containing 1 antibody, Nucleotide binding oligomerization domain leucine rich repeat and CARD domain containing 1 antibody, Nucleotide-binding oligomerization domain-containing protein 1 antibody, Protein Nod1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CARD4 recombinant protein (Position: M1-M160). Human CARD4 shares 82% amino acid (aa) sequence identity with mouse CARD4.E.coli-derived human CARD4 recombinant protein (Position: M1-M160). Human CARD4 shares 82% amino acid (aa) sequence identity with mouse CARD4.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.