CARD8 polyclonal, anti-human

Background:
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis.

Synonyms: NDPP, DACAR, DAKAR, NDPP1, TUCAN, CARDINAL

Cellular Location: Nucleus Cytoplasm

Immunogen:
Recombinant protein of human CARD8

Gene Symbol: CARD8

Gene ID: 22900

Swiss prot: Q9Y2G2

Calculated MW: 49kDa

Recommended dilution:
IHC 1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.