CARD9 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined.

Research Area: Cell Biology

Synonyms:
CANDF2, CARD9, CARD9, Caspase recruitment domain family member 9, Caspase recruitment domain-containing protein 9, hCARD9

Immunogen: Recombinant protein of human CARD9

Swissprot: Q9H257
Gene Accession: BC008877

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.8 mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-49408/sc-49405/sc-99054