CARMA1 (AL220) polyclonal, anti-human, mouse

Quantity: 50 µl

Description:
CARMA1 is involved in the costimulatory signal essential for T cell receptor (TCR)-mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK.

Synonyms:
CARD11, Bimp3, Caspase Recruitment Domain-containing Protein 11, CARD-containing MAGUK Protein 1

Isotype: Rabbit Polyclonal

Immunogen:
N-terminal human CARMA1 (aa 1-221 containing the CARD domain).

Form: Stabilized serum containing 0.02% sodium azide.

Specificity:
Recognizes human and mouse CARMA1. Detects a band of ~130Dka by Western blot.

Reactivity: human, mouse

Applications: Immunocytochemistry, Immunohistochemistry, Western Blot

Working DIlution: Optimal conditions must be determined individually for each application.

Storage: 2-8C immediate use, or -20C (aliquoted)